It's very much a given than those ventillation holes will allow dirt to accumulate inside any component that has them over a period of time. For me, i find those dirt more an annoyance than anything elese.
For sure opening your gears would invalidate the warranty. So if the warranty has expired and you are confident on how to open these things up, a vacuum clearner turned on reverse as a blower could make the insides a bit cleaner. Though I doubt such a ceremonious activity will improve the sound or performance of your gear. I think it matters more on CD/DVD players and cassette/VHS players with moving parts than amps, equalizers, processors and receivers. You could bring the units to a service center for something like this if you feel squeamish about dirt. Am just not sure if they charge so much for this.